In the course, basic (medical) microbiological theory is taught and illustrated with computer and laboratory experiments; these parts cover most of the course. With regard to (medical) microbiology, the negative effects of micro-organisms on humans will be covered (e.g. infectious diseases), but attention will also be paid to the positive effects on humans. Students will not only acquire theoretical knowledge from lectures and study books but also hands-on experience during workgroups and practicals. In the in-depth part of the course, attention will be paid to the contemporary systems-perspective within (medical) microbiological contexts. Systems-(micro)biological aspects will be treated in relation to the use of mathematical and computer models. In the practicals, students will acquire knowledge about experimental techniques and learn how to process and interpret the measurement and results they obtain. These laboratory practicals consist of up to nine "wet"- experiments and one "dry" computer-based experiment. By carrying out wet experiments, students also acquire practical and basic laboratory skills that are essential for their further studies. In addition, special lectures and seminars will focus on 'microbiological numeracy skills'. As part of the mathematical line of the first year, the use and construction of basic mathematical models in (medical) microbiology will be dealt with during Practical Computer Classes. Here the emphasis will be on obtaining a first understanding of model-based quantitative approaches.